Myasthenia gravis (MG) is a chronic autoimmune condition that causes symptoms like muscle weakness and double vision. Although joint pain isn’t usually listed as a symptom of MG, some people might experience joint issues due to other health conditions or the physical strain caused by weak muscles.

In this article, we’ll explore how MG might be linked to joint pain and ways to manage joint discomfort. Understanding the connection between MG and joint pain can help you live better with MG.

Does MG Cause Joint Pain Directly?

MG does not directly cause pain. The main symptom of MG is muscle weakness, not pain or discomfort. However, the strain of weak muscles can sometimes lead to joint problems. For example, if muscles aren’t working well, it can change how someone moves or walks, putting extra pressure on the joints. Over time, this may cause general aches and pains without a specific cause.

Can MG Treatments Cause Joint Pain?

Some treatments for MG, especially corticosteroids like prednisone, can cause joint pain as a side effect at higher doses. Steroids are immunosuppressive drugs often used to treat MG. However, long-term use of corticosteroids can lead to osteoporosis (weak bones) and the death of parts of the bone, especially in the hip. If you’re taking prednisone, it’s important to watch for side effects and talk to your health care provider if you experience joint pain.

Can Other Health Conditions Linked to MG Cause Joint Pain?

People with MG are at a higher risk of other autoimmune diseases that can cause joint pain. For example, rheumatoid arthritis (RA) and lupus can cause painful inflammation in the joints. If someone with MG also has RA or another condition that causes joint pain, the pain could be a symptom of the other condition rather than MG itself.

Unrelated Causes of Joint Pain

While MG may not be the direct cause of joint pain, several other possible causes of joint discomfort unrelated to MG should be considered. These include:

• Inflammation of the tendons (tendinitis) or the sacs that cushion joints (bursitis)
• Gout
• Osteoarthritis, which is normal wear and tear on joints that happens with age
• Runner’s knee or other overuse injuries
• Injuries such as sprains or fractures

Some situations or mental health issues can increase the risk of joint pain. These include stress, depression, or anxiety. Older adults and people with obesity are more likely to have joint pain.

It’s important to work with your health care provider to identify the cause of your joint pain and find the right treatment options.

Ways To Manage Joint Pain With MG

If you have MG and are experiencing joint pain, talk to your MG specialist and health care team about all your symptoms. They can examine you, order blood tests if needed, and help determine the cause of your joint pain. Based on their findings and your medical history, they might recommend treatments, refer you to a specialist, or suggest physical therapy.

Here are some general tips for managing joint pain, depending on its cause:

1. Use Ice Packs

Applying ice packs to sore joints can help reduce inflammation and numb the area, providing temporary relief. Use ice for short periods of time several times a day, and always wrap the ice pack in a cloth to protect your skin.

2. Try Heat Therapy

Heat therapy, such as heating pads or warm compresses, can also be comforting. Like ice therapy, heat therapy should only be used for short periods several times a day. Warm baths can also help ease joint pain. Consider adding Epsom salts for better relief.

3. Take Over-the-Counter Medications

Over-the-counter pain relievers like acetaminophen (Tylenol) can help reduce pain. Nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen (Advil) or naproxen (Aleve), can reduce both inflammation and pain. Always tell the pharmacist and your health care provider about your diagnosis of myasthenia gravis and any medications you are taking. Certain drugs can worsen symptoms of myasthenia gravis or interact with other medications you are taking, such as steroids and NSAIDs.

4. Try Topical Medications

Topical treatments, like creams, ointments, or gels, can be applied directly to painful joints for relief. Some of these can be bought without a prescription, while others may require one. Always inform your pharmacist about your MG.

5. Engage in Low-Impact Exercise

Gentle exercises like walking, swimming, or yoga can help keep your joints flexible and your muscles strong. Physical activity not only promotes better physical health but also mental well-being. Be sure to consult with your health care provider before starting any new exercise routine. They can give you tips on how to exercise safely with MG.

6. Get Physical Therapy

Your health care provider may refer you to a physical therapist. They can teach you exercises to strengthen the muscles around your joints, reduce pain, and improve your flexibility. A personalized exercise plan can help relieve joint pain without straining your muscles.

7. Consider Corticosteroid Injections

If you have severe joint pain, your health care provider may recommend corticosteroid injections. These injections are usually given directly into the painful joint. They reduce inflammation quickly and can provide relief from painful and swollen joints.

8. Maintain a Healthy Weight

Your health care provider may recommend weight loss, as extra weight can put additional strain on your joints, particularly your knees, hips, and back. Keeping a healthy weight through diet and exercise can reduce pressure on your joints and lessen pain.

9. Try Assistive Devices

If joint pain is making it difficult to move around, assistive devices (or supportive aids) like braces, canes, or shoe inserts can provide extra support and relieve pressure on painful joints. Your health care provider or physical therapist can help you choose the best options.

10. Ask About Prescription Pain Relievers

If over-the-counter painkillers or topical treatments aren’t enough, your health care provider may discuss stronger medications to help manage your joint pain. Keep in mind that some molecules may worsen your MG and should be avoided. Prescription pain relievers can reduce discomfort and make it easier to move around.

Communicate With Your MG Specialist

Living with MG can be challenging, and joint pain can make it even harder. While MG doesn’t directly cause joint pain, there are many reasons someone with MG might experience it, such as muscle weakness or other health conditions. The good news is there are ways to manage joint pain. By working with your neurologist and using treatments like ice or heat therapy, low-impact exercise, physical therapy, or medication, you can find relief and improve your quality of life. Always talk to your health care provider about any new symptoms, and together, you can create a plan to keep you feeling your best.

Talk With Others Who Understand

On MGteam, the social network for people living with myasthenia gravis and their loved ones, members come together to ask questions, give advice, and share their stories with others who understand life with myasthenia gravis.

Are you living with joint pain with myasthenia gravis? Which joints hurt, and have you discussed the pain with your doctors? Share your experience in the comments below, or start a conversation by posting on your Activities page.