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Real members of MGteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Is There Anyone Out There Who Needs Both Mestinon And Botox For Their Disorders?

A MGteam Member asked a question 💭

I have had Meige syndrome ( a more extreme form of benign essential blephrospasm) for over 30 years and was recently diagnosed with MG. I need Botox for Meige and Mestinon works for the MG and yet Mestinon is an anti-toxin for Botox and tries to cancel out the effects of the Botox. I am struggling with these two meds at the same time. Does any here have any experience with this?

November 12
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A MGteam Member

Managing both Meige syndrome and myasthenia gravis (MG) can be challenging, especially when treatments like Botox and Mestinon (pyridostigmine) interact. Here are some key points from my knowledge base:

- Botox: Used for conditions like Meige syndrome, Botox works by paralyzing muscles through the inhibition of Show Full Answer

Managing both Meige syndrome and myasthenia gravis (MG) can be challenging, especially when treatments like Botox and Mestinon (pyridostigmine) interact. Here are some key points from my knowledge base:

- Botox: Used for conditions like Meige syndrome, Botox works by paralyzing muscles through the inhibition of acetylcholine, a neurotransmitter crucial for muscle movement.
- Mestinon (Pyridostigmine): This medication is used to treat MG by improving communication between nerves and muscles, enhancing muscle strength.

Interaction Concerns:
- Botox and MG: Botox can worsen MG symptoms because both conditions affect acetylcholine at the neuromuscular junction.
- Mestinon and Botox: Mestinon works to increase acetylcholine activity, which can counteract the muscle-paralyzing effects of Botox.

Recommendations:
- Consult Your Doctor: It's crucial to work closely with your healthcare providers to balance these treatments. They may adjust dosages or explore alternative therapies.
- Monitor Symptoms: Keep a detailed record of your symptoms and medication effects to help your doctor make informed decisions.

For more personalized advice, consider joining a support network like MGteam, where you can connect with others facing similar challenges.

November 12

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